Lymph node cancer or lymphomas (flash) is a type of cancer that grows by mutations lymphocyte cells (a type of white blood cells) previously normal. This resulted in abnormal nenjadi malignant cells. Like normal lymphocytes, malignant lymphocytes can grow in discrete organs in the body along with lymph nodes, spleen, sum-sum bones, blood or other organs.
There are two kinds of lymphatic system cancers: Hodgkin's disease and Non-Hodgkin's lymphoma (Nhl) (flash). Nhl is a group of diseases linked malignancy that Affects the lymphatic system.
Microscope
Lymphatic System
The lymphatic system is an leading part of the immune system plays a key role in the body's natural defenses against infection and cancer. The lymphatic fluid is a white liquid like milk protein, fat, and lymphocytes (white blood cells) that all flow throughout the body via the lymphatic vessels. There are two kinds of cells are lymphocytes: B cells and T cells
B cells help safe the body against bacteria by development antibodies that assault and destroy bacteria.
Symptoms and signs
Nhl signs and symptoms consist of swollen lymph nodes (in the neck, armpit or groin). Gland enlargement was able to start with symptoms of weight loss, fever, night sweats. There is no early detection test for the Nhl. If the above symptoms are found, it is advisable to go to the physician for additional examination.
Causes Nhl
The exact cause is unknown. Four possible causes are: genetics, immune system disorders, viral or bacterial infections (Hiv, Hcv, Ebv, Helicobacter Sp) and environmental toxins (herbicides, preservatives and chemical dyes).
Types of Nhl
There are more than 30 sub-types of Nhl are distinct (90 percent of type B cells), which can be grouped agreeing to some classification guidelines. Classification is to consider several factors like appearance under a microscope, the size, speed of increase and organ affected.
Generally recognized some form of Nhl that is very aggressive (fast growing), intermediate and indolent (slow growing). The estimation was carried out with a microscope by a pathologist in the laboratory.
Medical
Nhl cores currently treatments consist of chemotherapy, monoclonal antibody therapy, radiation, biological therapy and Transplantation of bone-sum-sum. Determining which type of therapy depends taken very personel health of patients and depends on 3 main factors:
1. Stadium
2. Size
3. Degree of malignancy
Lymphoma Aggressive (intermediate / high degree of malignancy) to grow and spread fast in the body and if left without treatment can kill within 6 months. Life Expectancy ranges from an average of 5 years with about 30-40% Healed. Patients who are diagnosed early and treated immediately are more likely to accomplish unblemished remission and rarely experienced a Relapse. Because there is possible for recovery, it is ordinarily more aggressive treatment.
Standard therapy includes previous appropriate Chop chemotherapy and / or high-dose chemotherapy and Transplantation sum-sum. Recently, the use of rituximab plus appropriate chemotherapy has been recommended by European researchers who treat aggressive Nhl based on a test that shows Clinicians postponement of Life Expectancy of patients when treated with rituximab + Chop compared to Chop only.
Indolent lymphoma (low degree of malignancy) grow slowly so early diagnostics becomes more difficult. Patients can survive for years with this disease, but no appropriate treatment can not cure. Usually, patients acknowledge well to preliminary therapy, but it is very possible the cancer grew back.
Patients with indolent lymphoma can get the therapy for five to six times throughout their lives. However, patients ordinarily acknowledge to lower the therapy. Life Expectancy in this type of lymphoma, where patients often defeated by the disease or complications that Arise, fluctuating between six months.
Linfoma developments in Indonesia is quite fast. Based on the number of patients seeking help at the Rscm and Dharmais Hospital Cancer Foundation, an average of 300 citizen each year. Whereas in 2005 only 150 citizen per year.
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